Streptococcus, Group B

Antibiotic
% Susceptible
2010
% Susceptible
2012
% Susceptible
2014
% Susceptible
2016
% Susceptible
2018
Ampicillin
100
 100 100 100 100
Azithromycin
+/-
 +/-
53
 + 43
Aztreonam
-
 -
-
 - -
Cefazolin
100
 100
100
100 100
Cefepime
+
 +
+
+ +
Ceftazidime
+
 +
+
 + +
Ceftriaxone
100
 100
100
 100 100
Cefuroxime
+
 +
+
+ +
Ciprofloxacin
+/-
 +/-
+/-
 +/- +/-
Clarithromycin
+
 +
+
 + +
Clindamycin
62
 67
62
 67 55
Doxycycline
-
 -
15
 - -
Erythromycin
50
 62
53
 55 +/-
Gentamicin
-
 -
-
 - -
Imipenem
+
 +
+
 + +
Levofloxacin 98 99 100 100 100
Meropenem + + + + +
Moxifloxacin + + + + +
Nitrofurantoin & & & & &
Oxacillin/Naf + + + + +
Penicillin 100 100 100 100 99
Piperacillin + + + + +
Piperacillin/tazo + + + + +
Ticarcillin/Clav + + + + +
Tobramycin - - - - -
TMP/SMX - - - - -
Unasyn/Aug + + + + +
Vancomycin + 100 100 100 100
       
# Tested 201 158 101 103 91

Comments:   Beta streptococci remain reliably susceptible to beta lactam antibiotics including penicillin

 

Numeric data represent local susceptibility data.
(+) = usually effective or >60% susceptible; (+/-) = clinical trials lacking or 30-60% susceptible; (-) = not effective clinically or <30% susceptible - Adapted with permission from The Sanford Guide to Antimicrobial Therapy
(*) Local (non-Sanford Guide) opinion
(S) = synergistic with penicillin/ampicillin;
(&) nitrofurantoin only useful for lower tract urinary tract infections