Staphylococcus aureus, methicillin sensitive

Antibiotic
% Susceptible
2010
% Susceptible
2012
% Susceptible
2014
% Susceptible
2016
% Susceptible
2018
Ampicillin
-
 - - - -
Azithromycin
+
 +
+
 + +
Aztreonam
-
 -
-
 - -
Cefazolin
100
 100
100
100 100
Cefepime
+
 +
+
+ +
Ceftazidime
+/-
 +/-
+/-
 +/- +/-
Ceftriaxone
100
 100
100
 100 100
Cefuroxime
+
 +
+
+ +
Ciprofloxacin
83
 81
85
 80 76
Clarithromycin
+
 +
+
 + +
Clindamycin
83
 87
87
 89 86
Doxycycline
95
 95
97
 96 94
Erythromycin
65
 66
70
 69 63
Gentamicin
+
 +
+
 + +
Imipenem
+
 +
+
 + +
Levofloxacin 85 83 87 81 77
Meropenem + + + + +
Moxifloxacin 97 96 96 97 96
Nitrofurantoin 99& 99& 99& 99& 99&
Oxacillin/Naf 100 100 100 100 100
Penicillin 2 0 0 0 0
Piperacillin - - - - -
Piperacillin/tazo + + + + +
Ticarcillin/Clav + + + + +
Tobramycin + + + + +
TMP/SMX 98 99 100 100 100
Unasyn/Aug 100 100 100 100 100
Vancomycin 100 100 100 100 100
       
# Tested 1692 1381 1561 1342 1241

Comments:   Fluoroquinolone use as first line agents against Staph aureus is discouraged.

 

Numeric data represent local susceptibility data.
(+) = usually effective or >60% susceptible; (+/-) = clinical trials lacking or 30-60% susceptible; (-) = not effective clinically or <30% susceptible - Adapted with permission from The Sanford Guide to Antimicrobial Therapy
(*) Local (non-Sanford Guide) opinion
(S) = synergistic with penicillin/ampicillin;
(&) nitrofurantoin only useful for lower tract urinary tract infections