Samaritan Infectious Disease - Antibiotic Table

Antibiotic	Indications	Adverse Reactions	Comments
Ampicillin	Sinusitis Enterococci Listeria Lyme disease	Allergic reactions Rash with inadvertant Rx of infectious mononucleosis	Amoxicillin is preferred to ampicillin for oral use as it is more bioavailable
Azithromycin	Community acquired pneumonia Atypical pneumonia Non-tuberculous mycobacterial infections Pertussis Gonorrhea	Diarrhea QTc prolongation	Long half life; fewer drug interactions than other macrolides
Aztreonam	Serious aerobic gram negative infections	Diarrhea	Ideal for use in cases of severe beta-lactam allergy: no GPC or anaerobic activity
Cefazolin	Staph aureus infections Cellulitis Surgical prophylaxis	Rash/allergy	1st gen cephalosporin - generally has better GPC coverage, lesser GNR coverage than later generations
Cefepime	Broad spectrum agent Pseudomonas Neutropenic fever	Rash/allergy	4th generation cephalosporin; excellent Staph aureus (non-MRSA) and GNR coverage
Ceftaroline	Complicated skin and soft tissue infections Community acquired pneumonia	Nausea, vomiting Rash/allergy	MRSA activity; not reliable for pseudomonas
Ceftazidime	Serious gram negative infections Neutropenic fever	Rash/allergy	3rd generation cephalosporin; relatively poor activity against GPC
Ceftazidime/avi	Complicated intra-abdominal infections Complicated urinary tract infections	Nausea, vomiting Anxiety Rash/allergy	Active against GNR including ESBL and CRE producing; Poor anaerobic activity. Add metronidazole for intra-abdominal infections
Ceftolozane/tazo	Complicated intra-abdominal infections Complicated urinary tract infections	Nausea, vomiting Rash/allergy	Novel, advanced generation cephalosporin; active against many ESBL forming enterobacteriacae and may be active against MDR P. aeruginosa

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Drug Information provided above is not comprehensive. For complete information about these antibiotics consult a pharmacist or a comprehensive drug reference.